Pharmaceutical Raw Materials Powder Pregabalin/Lyrica CAS 148553-50-8
description
| Product Name: pregabalin | wj1@gzwjsw.com whatsapp +8615512123605 signal +66980528100 |
| Synonyms: | 3(S)-(AMINOMETHYL)-5-METHYLHEXANOIC ACID;(3S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID;PREGABALIN;Pregablin;3-(Aminomethyl)-5-methyl-hexanoic acid;PREDNISOLONESODIUMPHOSPHATE;(R)-Pregabalin;(S)-Pregabalin |
| CAS: | 148553-50-8 |
| MF: | C8H17NO2 |
| MW: | 159.23 |
| EINECS: | 604-639-1 |
| Mol File: | 148553-50-8.mol |
Product Description
Nervous System API with Pain Relieve Pregabalin CAS 148553-50-8
Pregabalin Quick detail:
| Name | Pregabalin |
| other name | LYRICA |
| Pregabalin Cas No. | 148553-50-8 |
| Pregabalin Molecular formula | C8H17NO2 |
| Pregabalin Molecular weight | 159.23 |
| Pregabalin Purity | 99% |
| Pregabalin Grade | Pharmaceutical grade |
| Pregabalin Appearance | White Crystal Powder |
| Standard | USP standard |
| Package | 25kg/drum |
| Usage | New antiepileptic drugs. Used in the treatment of peripheral neuropathy, or partial seizures |
| 28578-16-7 | PMK ethyl glycidate | High temperature yellow oily/low temperature yellow solid |
| 28578-16-7 | PMK ethyl glycidate | White powder |
| 28578-16-7 | PMK ethyl glycidate | Yellow powder |
| 2079878-75-2 | 2-(2-Chlorophenyl)-5-nitrocyclohexanone | Alternative 2f, white crystal particles |
| 20320-59-6 | Diethyl(phenylacetyl)malonate BMK | Yellow liquid |
| 288573-56-8 | 1-BOC-4-(4-FLUORO-PHENYLAMINO)-PIPERIDINEKS-0037 | White crystalline powder |
| 91393-49-6 | 2-(2-chlorophenyl)cyclohexanone | White puffed powder |
| 10250-27-8 | 2-Benzylamino-2-methyl-1-propanol | White/light yellow powder powder |
| 79099-07-3 | N-(tert-Butoxycarbonyl)-4-piperidone | White or light yellow powder |
| 102-97-6 | N-Isopropylbenzylamine | White crystal |
| 5413-05-8 | Ethyl 2-phenylacetoacetate | White puffed powder |
| 1451-82-7 | 2-Bromo-4'-methylpropiophenone | White puffed powder |
| 593-51-1 | Methylamine hydrochlorideMEDA | White crystal |
| 613-93-4 | N-METHYLBENZAMIDE | White puffed powder |
| 119276-01-6 | Protonitazene (hydrochloride) | Brown block |
| Substitution (etiazepine ) | ||
| 71368-80-4 | Bromazolam | Light pink powder |
| 49851-31-2 | 2-Bromo-1-Phenyl-Pentan-1-One | Yellow liquid |
| 139755-83-2 | Sildenafil | White flash crystalline powder |
| 52190-28-0 | 1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one | Brown block |
| 5449-12-7 | 2-methyl-3-phenyl-oxirane-2-carboxylic acid | White or light yellow powder |
| 40064-34-4 | 4,4-Piperidinediol hydrochloride | Off-white or light yellow powder |
| 19099-93-5 | 1-Cbz-4-Piperidone | White powder |
| 877-37-2 | 2-bromo-4-chloropropiophenone | White powder |
| 1451-83-8 | 2-Bromo-1-Phenyl-1-Butanone | White powder |
| 236117-38-7 | 2-iodo-1-p-tolylpropan-1-one | Yellow powder |
| 5337-93-9 | 4-Methylpropiophenone | Yellow liquid |
| 103-81-1 | 2-Phenylacetamide | White powder, soft |
| 123-39-7 | N-methylformamide | Colorless transparent liquid |
| 124878-55-3 | 2-iodo-1-phenyl-pentane-1-one | Yellow liquid |
| 14176-50-2 | Tiletamine Hydrochloride | White crystalline powder |
| 443998-65-0 | 1-BOC-4-(4-BROMO-PHENYLAMINO)-PIPERIDINE | White powder |
| 28281-49-4 | 3,4-(METHYLENEDIOXY)PROPIOPHENONE | White powder |
Medical uses:
Seizures
Pregabalin is useful when added to other treatments, when those other treatments are not controling partial epilepsy. Its use alone is less effective than some other seizure medications. It is unclear how it compares to gabapentin for this use.
Neuropathic pain
The European Federation of Neurological Societies recommends pregabalin as a first line agent for the treatment of pain associated with diabetic neuropathy, post-herpetic neuralgia, and central neuropathic pain. A minority obtain substantial benefit, and a larger number obtain moderate benefit. Other first line agents, including gabapentinand tricyclic antidepressants, are given equal weight as first line agents, and unlike pregabalin, are available as less expensive generics.
Pregabalin is not recommended for certain other types of neuropathic pain such as pain that of trigeminal neuralgia or HIV infection and its use in cancer-associated neuropathic pain is controversial.There is no evidence for its use in the prevention of migraines and gabapentin has been found not to be useful. It has been examined for the prevention of post-surgical chronic pain, but its utility for this purpose is controversial.
Anxiety disorders
Therapeutic effects of pregabalin appear after 1 week of use and is similar in effectiveness to venlafaxine, but pregabalin has demonstrated superiority by producing more consistent therapeutic effects for psychic and somatic anxiety symptoms.Long-term trials have shown continued effectiveness without the development of tolerance, and, in addition, , it has a beneficial effect on sleep and sleep architecture, characterized by the enhancement of slow-wave sleep. and produces less severe cognitive and psychomotor impairment;
Seizures
Pregabalin is useful when added to other treatments, when those other treatments are not controling partial epilepsy. Its use alone is less effective than some other seizure medications. It is unclear how it compares to gabapentin for this use.
Neuropathic pain
The European Federation of Neurological Societies recommends pregabalin as a first line agent for the treatment of pain associated with diabetic neuropathy, post-herpetic neuralgia, and central neuropathic pain. A minority obtain substantial benefit, and a larger number obtain moderate benefit. Other first line agents, including gabapentinand tricyclic antidepressants, are given equal weight as first line agents, and unlike pregabalin, are available as less expensive generics.
Pregabalin is not recommended for certain other types of neuropathic pain such as pain that of trigeminal neuralgia or HIV infection and its use in cancer-associated neuropathic pain is controversial.There is no evidence for its use in the prevention of migraines and gabapentin has been found not to be useful. It has been examined for the prevention of post-surgical chronic pain, but its utility for this purpose is controversial.
Anxiety disorders
Therapeutic effects of pregabalin appear after 1 week of use and is similar in effectiveness to venlafaxine, but pregabalin has demonstrated superiority by producing more consistent therapeutic effects for psychic and somatic anxiety symptoms.Long-term trials have shown continued effectiveness without the development of tolerance, and, in addition, , it has a beneficial effect on sleep and sleep architecture, characterized by the enhancement of slow-wave sleep. and produces less severe cognitive and psychomotor impairment;
Company Profile
Guangzhou Wanjiang Biotechnology Co., Ltd. is a young chemical enterprise full of vitality, potential and comprehensive
strength.The company is located in the center of politics, military, economy, culture and science and education in South China.We are a professional manufacturer engaged in the research, development, production, sales and service of surfactants, biological agents, organic chemistry, oilfield chemicals and disinfectant raw materials.We can offer a wide range of products to meet the changing needs of the market.Custom orders are welcome.We are committed to strict quality control and thoughtful customer service, and our experienced staff are always available to discuss your requirements and ensure complete customer satisfaction.With an annual production capacity of 10,000 tons/year, we can easily meet your large orders.If you are interested in any of our products or would like to place a custom order, please contact us.We will do our best to meet your needs. whatsapp+8615512123605
strength.The company is located in the center of politics, military, economy, culture and science and education in South China.We are a professional manufacturer engaged in the research, development, production, sales and service of surfactants, biological agents, organic chemistry, oilfield chemicals and disinfectant raw materials.We can offer a wide range of products to meet the changing needs of the market.Custom orders are welcome.We are committed to strict quality control and thoughtful customer service, and our experienced staff are always available to discuss your requirements and ensure complete customer satisfaction.With an annual production capacity of 10,000 tons/year, we can easily meet your large orders.If you are interested in any of our products or would like to place a custom order, please contact us.We will do our best to meet your needs. whatsapp+8615512123605
FAQ
1. who are we?
We are based in Guangdong, China, start from 2021,sell to North America(25.00%),South America(25.00%),Central America(25.00%),Eastern Europe(5.00%),Southeast Asia(5.00%),Mid East(5.00%),Western Europe(5.00%),Northern Europe(5.00%). There are total about 101-200 people in our office.
2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;
3.what can you buy from us?
btms50,80532-66-7,288573-56-8,5413-05-8,5449-12-7 ,
4. why should you buy from us not from other suppliers?
Our products are of high quality and competitive price, and we are highly recognized by our customers with high quality materials and excellent service.We are willing to work together with our business partners.
We are based in Guangdong, China, start from 2021,sell to North America(25.00%),South America(25.00%),Central America(25.00%),Eastern Europe(5.00%),Southeast Asia(5.00%),Mid East(5.00%),Western Europe(5.00%),Northern Europe(5.00%). There are total about 101-200 people in our office.
2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;
3.what can you buy from us?
btms50,80532-66-7,288573-56-8,5413-05-8,5449-12-7 ,
4. why should you buy from us not from other suppliers?
Our products are of high quality and competitive price, and we are highly recognized by our customers with high quality materials and excellent service.We are willing to work together with our business partners.
Pregabalin COA:
| ITEMS | STANDARDS | RESULTS |
| Appearance | A white to off white powder | White powder |
| Identification | A. Meets the requirement | Complies |
| B. IR: similar to Reference Substance | Complies | |
| Loss on drying | ≤0.5% | 0.21% |
| Specific Rotation | +10.0°~+13.0° | +10.8° |
| Related Substances | Any single impurity ≤0.1% Total impurity ≤0.8% | 0.05% 0.10% |
| Purity By HPLC R-isomer | ≤0.15% | 0.10 |
| Residue on ignition | ≤0.1% | 0.05% |
| Residual solvents | Isopropyl alcohol ≤5000ppm Ethyl Acetate ≤5000ppm | 150ppm 250ppm |
| Heavy metals | ≤10ppm | Complies |
| Chlorides | ≤0.05% | Complies |
| Assay | 98%~102.0% | 99.8% |
| Conclusion | Analyse according to Factory Standard , Conform |
wj1@gzwjsw.com
whatsapp +8615512123605
signal +66980528100
wickr me , wanjiang