Rats and mice often enter Premises, schools, Sewage system and warehouses in search of food and shelter. The most common rodent pests are the commensally rats and mice. These are old world rodents that have adapted to live with humans. They include the roof rat, Norway rat, and Earth. Rats and mice consume or contaminate large quantities of food and damage structures, house mouse These commensally rodents have been carried by humans to every corner of the stored clothing, and documents. They also serve as reservoirs or vectors of numerous diseases, Such as rat bite Fever, Leptospirosis (Weil’s disease), Murine typhus, Rickettsialpox, Plague, Trichinosis, Typhoid, Dysentery, Salmonellosis, Hymenolepiasis, and Choriomeningitis.