Ranitidine 150 mg, formerly a popular H2 blocker, was widely used to relieve acid reflux by reducing stomach acid production. It was typically taken once or twice daily, with or without food. For mild to moderate symptoms, a dose of 150 mg twice daily or 300 mg at bedtime was common. To maximize its effect, users were advised to take it 30–60 minutes before meals or when symptoms were expected, such as before lying down.
While effective, Ranitidine was withdrawn from many markets after concerns about NDMA contamination, a potential cancer risk. As a result, it is no longer widely recommended, and safer alternatives like famotidine or omeprazole are now used instead.